CBD Associated With Decreased Daytime Fatigue In Croatian Clinical Trial

It’s fairly common for someone to feel fatigued as the day goes on, especially when it comes to suffering patients who may already struggle with fatigue due to their health condition(s). Even for non-suffering patients, the ‘two-thirty feeling’ can be real when tiredness sets in around the middle of the afternoon.

A number of products and services profess to boost energy throughout the day, with varying levels of effectiveness. Many energy-boosting products contain large amounts of added sugar and other additives that are not always healthy.

Researchers in Croatia recently conducted a clinical trial to determine if cannabidiol (CBD) can be effective at reducing daytime fatigue. Below is more information about the results of the clinical trial via a news release from NORML:

Split, Croatia: CBD administration is associated with decreased daytime fatigue and improved psychological well-being, according to randomized placebo-controlled data published in the journal Cannabis and Cannabinoid Research.

A team of Croatian researchers assessed the use of CBD versus placebo on participants’ quality of life. Subjects consumed either CBD or placebo for five-week intervals.

“Five-week administration of CBD, but not of placebo, resulted in improvement of ESS [Epworth sleepiness scale] score as well as fatigue/vitality and psychological well-being,” investigators concluded. Although subjects reported reduced incidents of daytime sleepiness, they did not similarly report improvements in their overall sleep quality.

Prior studies have reported that CBD dosing before bedtime is associated with improved sleep quality in patients with a history of sleep disturbances.

Full text of the study, “Chronic cannabidiol administration mitigates excessive daytime sleepiness and fatigue in patients with primary hypertension: insights from a randomized crossover trial,” appears in Cannabis and Cannabinoid Research.