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CBD Effectively Treats Acute Dental Pain In Randomized Clinical Trial

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The cannabis plant contains dozens of cannabinoids, each with its own characteristics and potential to provide wellness benefits. For many decades tetrahydrocannabinol (THC) was the focus of much of the cannabis research conducted by scientists.

However, in recent years other cannabinoids have risen in popularity, and that has shifted some of the focus of cannabis researchers. Cannabidiol (CBD) is a very popular cannabinoid these days among consumers, patients, product developers, and researchers.

According to a recent randomized clinical trial conducted in Scotland, CBD can effectively treat acute dental pain. Below is more information about the study via a news release from NORML:

Kilmarnock, Scotland: The administration of a purified formulation of plant-derived CBD (aka Epidiolex) provides significant short-term relief to patients suffering from acute toothaches, according to placebo-controlled clinical trial data published in the journal Evidence-Based Dentistry.

A pair of Scottish scientists assessed the use of Epidiolex versus placebo in 61 patients with moderate-to-severe dental pain. Forty patients received CBD in doses of either 10 or 20 mgs. Twenty-one subjects received a placebo. Patients’ pain was monitored for three hours following dosing.

Patients who consumed CBD, on average, experienced a greater than 50 percent reduction in their pain, investigators reported. By contrast, those receiving placebo experienced a 37.5 percent decrease in pain.

“Based on this randomized clinical trial, pure CBD drug Epidiolex demonstrates effective analgesia against acute toothache,” the study’s authors concluded.

The US Food & Drug Administration approved the prescription use of Epidiolex as an anti-epileptic drug in 2018. The DEA removed Epidiolex from the Controlled Substances Act in 2020.

Full text of the study, “Cannabidiol – an effective analgesic for toothache,” appears in Evidence-Based Dentistry.